Pantothenic acid is absorbed in the intestine and delivered directly into the bloodstream by active transport (and possibly simple diffusion at higher doses). These forms are converted to pantothenic acid by digestive enzymes (nucleosidases, peptidases, and phosphorylases) in the intestinal lumen and intestinal cells. About 85% of dietary pantothenic acid is in the form of CoA or phosphopantetheine. Ī wide variety of plant and animal foods contain pantothenic acid. Acyl carrier protein’s main role is in fatty acid synthesis. CoA is essential for fatty acid synthesis and degradation, transfer of acetyl and acyl groups, and a multitude of other anabolic and catabolic processes. The main function of this water-soluble B vitamin is in the synthesis of coenzyme A (CoA) and acyl carrier protein. Pantothenic acid (also known as vitamin B5) is an essential nutrient that is naturally present in some foods, added to others, and available as a dietary supplement. For a general overview of Pantothenic Acid, see our consumer fact sheet on Pantothenic Acid. This is a fact sheet intended for health professionals. Health Risks from Excessive Pantothenic Acid.Groups at Risk of Pantothenic Acid Inadequacy.

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